Tropical medicine & international health : TM & IH
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Trop. Med. Int. Health · Feb 2010
Coagulation disorders in patients with severe leptospirosis are associated with severe bleeding and mortality.
To determine the involvement of coagulation in bleeding and poor outcome in patients with severe leptospirosis. ⋯ The coagulation system was strongly activated in patients with leptospirosis. This was more pronounced in the deceased and in patients with severe bleeding than in than the survivors and in those without severe bleeding.
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Trop. Med. Int. Health · Jan 2010
Provider-initiated HIV testing for paediatric inpatients and their caretakers is feasible and acceptable.
Early diagnosis of HIV-infected children remains a major challenge in Africa. Children who are hospitalised represent an opportunity for HIV diagnosis and appropriate treatment. We introduced HIV Counselling and Testing (HCT) for hospitalised children and their caretakers in Mulago teaching hospital in Uganda to assess its feasibility. ⋯ HCT for hospitalized children and their caretakers identified a significant number of HIV infected children and caretakers. More than half of the children had advanced HIV disease. More intensive efforts are needed to ensure earlier diagnosis and linkage to care for HIV infected children.
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Trop. Med. Int. Health · Oct 2009
ReviewEpidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: a comprehensive review.
To identify the gaps of knowledge and highlight the challenges and opportunities for controlling cervical cancer in sub-Saharan Africa (SSA). ⋯ Additional data are needed to strengthen ICC as a public health priority to introduce, implement and sustain effective cervical cancer control in Africa.
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Trop. Med. Int. Health · Sep 2009
ReviewA comprehensive approach to risk assessment and surveillance guiding public health interventions.
Tools are required to identify 'multi-endemic' population segments - in order to benefit the most vulnerable people and to make public health interventions cost-effective. The article suggests a comprehensive risk assessment and surveillance system approach based on a combination of epidemiological, environmental and social determinants. Such a cross-disciplinary approach will combine the advantages of forecasting upcoming disease 'hot spots' with provision of evidence for long-term planning under more stable conditions, and it may in principle apply to any combination of public health problems depending on the local context.