International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
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To evaluate the value of plasma fibronectin (pFN) as a diagnostic marker of sepsis. ⋯ Plasma FN appears to act as a marker of sepsis in that patients showed diminished pFN levels. Along with other clinical and laboratory variables, the use of this marker would allow a rapid diagnosis of sepsis and limit the number of blood cultures to be processed and the number of antibiotic prescriptions, particularly when symptoms are insidious and diagnosis is doubtful. We propose further and more complex studies using a higher number of patients.