The journal of obstetrics and gynaecology research
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J. Obstet. Gynaecol. Res. · May 2014
Review Meta Analysis Comparative StudyLetrozole versus clomiphene citrate for unexplained infertility: a systematic review and meta-analysis.
The objective of this study is to investigate and compare the effectiveness of letrozole and clomiphene citrate for improving fertility outcomes, including pregnancy rate, miscarriage rate, multiple pregnancy rate, and incidence rate of adverse events, number of dominant follicles, endometrial thickness at hCG day and serum E2 on hCG day. MEDLINE, EMBASE, CENTRAL, CNKI and CBMdisc databases were searched up to March 2013. Randomized controlled trials comparing letrozole with clomiphene in women with unexplained infertility were included. ⋯ The results of this study conclude that letrozole is as effective as clomiphene in women with unexplained infertility. Letrozole at a dose of 2.5 mg seems more effective. Further high-quality studies assessing the possible effectiveness of letrozole in selected groups of patients are warranted.
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J. Obstet. Gynaecol. Res. · May 2014
Randomized Controlled TrialTranscutaneous electrical nerve stimulation for the relief of post-partum uterine contraction pain during breast-feeding: a randomized clinical trial.
To evaluate transcutaneous electrical nerve stimulation (TENS) used to relieve uterine contraction pain during breast-feeding in multiparous women. ⋯ TENS was found to be effective in reducing post-partum uterine contraction pain during breast-feeding.
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J. Obstet. Gynaecol. Res. · May 2014
Anterior placentation as a risk factor for massive hemorrhage during cesarean section in patients with placenta previa.
In placenta previa (PP), anterior placentation, compared with posterior placentation, is reported to more frequently cause massive hemorrhage during cesarean section (CS). Whether this is due to the high incidence of placenta accreta, previous CS, or a transplacental approach in anterior placenta is unclear. We attempted to clarify this issue. ⋯ Anterior placentation, namely, the placenta with a longer os-placental edge distance in the anterior wall than in the posterior wall, was a risk of massive hemorrhage during CS for PP.