The journal of obstetrics and gynaecology research
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J. Obstet. Gynaecol. Res. · Jan 2018
Cost effectiveness analysis of carbetocin during cesarean section in a high volume maternity unit.
To evaluate the cost effectiveness of carbetocin compared to oxytocin when used as prophylaxis against post-partum hemorrhage (PPH) during cesarean deliveries. ⋯ Reduction in retreatment, staffing requirements, transfusion and potential medication errors mitigates the higher index cost of carbetocin. From a pharmacoeconomic perspective, in the context of cesarean section, carbetocin was cost effective as prophylaxis against PPH. Ultimately, the relative value placed on the outcomes above and the individual unit's resources would influence the choice of uterotonic.
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J. Obstet. Gynaecol. Res. · Jan 2018
Increased maternal insulin resistance promotes placental growth and decreases placental efficiency in pregnancies with obesity and gestational diabetes mellitus.
Homeostasis model assessment for insulin resistance (HOMA-IR) was measured during pregnancy to analyze placental weight and efficiency in relation to maternal insulin resistance. ⋯ Increased maternal insulin resistance promoted placental growth and inhibited placental efficiency. Maternal insulin resistance may be one of the pathophysiological conditions responsible for altered placental size and function in pregnancies with obesity and GDM.
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J. Obstet. Gynaecol. Res. · Jan 2018
Scoring model to predict massive post-partum bleeding in pregnancies with placenta previa: A retrospective cohort study.
We aimed to identify factors associated with massive post-partum bleeding in pregnancies with placenta previa and to establish a scoring model to predict post-partum severe bleeding. ⋯ Our scoring model might provide useful information for prediction of massive post-partum bleeding in pregnancies with placenta previa.