Respirology : official journal of the Asian Pacific Society of Respirology
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Randomized Controlled Trial
Non-invasive ventilation improves peripheral oxygen saturation and reduces fatigability of quadriceps in patients with COPD.
Non-invasive ventilation (NIV) might improve peripheral muscle function and exercise capacity in severely disabled patients. This study evaluated the physiological impact of NIV on isokinetic concentric strength and endurance of lower limb muscles in patients with severe COPD. ⋯ BV improved SpO(2) and reduced the fatigability of the quadriceps muscle in patients with severe COPD. These results support the need for further evaluation of BV as adjunct during high-intensity strength exercise training in these patients.