Archives of disease in childhood
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We sought to measure the diagnostic accuracy of D-dimer in children with suspected pulmonary embolism (PE). ⋯ D-dimer is currently ordered in children for suspected PE in the emergency care setting, mostly in teenagers. The observed lower limit 95% CIs of 89% and 54% for diagnostic sensitivity and the specificity, respectively, suggest if used in patients with low-clinical probability, a normal D-dimer can safely exclude PE in children.