The veterinary journal
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The veterinary journal · Oct 2012
Randomized Controlled TrialEffects of a stepwise lung recruitment manoeuvre and positive end-expiratory pressure on lung compliance and arterial blood oxygenation in healthy dogs.
This study was performed to evaluate the effects of a stepwise lung recruitment manoeuvre (RM) on dynamic lung compliance (Cdyn) and gas exchange in mechanically ventilated healthy dogs. Fourteen healthy adult dogs, scheduled for elective surgery in dorsal recumbency were employed. After anaesthetic induction, dogs were mechanically ventilated in a volume-controlled mode (tidal volume, VT=10 mL/kg); positive end-expiratory pressure (PEEP)=0 cm H(2)O; oxygen inspired fraction (FiO(2))=0.4 for 30 min (baseline). ⋯ Cdyn increased in the RM group (183 ± 30% and 165 ± 24% at 20 and 60 min, respectively; P=0.000). The baseline partial pressure of arterial oxygen to FiO(2) ratio (PaO(2)/FiO(2) ratio) did not change in the control group, but was higher in the RM group (527 ± 41 mm Hg and 511 ± 46 mm Hg at 20 and 60 min, respectively; baseline 371 ± 34 mm Hg, P<0.001). In conclusion, a stepwise RM followed by the use of PEEP improves Cdyn and oxygenation in mechanically ventilated healthy dogs.