The veterinary journal
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The veterinary journal · Sep 2013
Randomized Controlled TrialComparison of intrarectal ozone, ozone administered in acupoints and meloxicam for postoperative analgesia in bitches undergoing ovariohysterectomy.
Since all analgesics currently available for use in dogs have been associated with some adverse effects, the search for an effective analgesic that does not cause harm is important. This study investigated the postoperative analgesic effects of ozone administered either intrarectally or into acupoints in bitches undergoing ovariohysterectomy (OH). Twenty-four healthy adult bitches were randomly assigned to one of the three treatments 10 min after sedation, as follows: 0.2mg/kg of intramuscular (IM) meloxicam (M); rectal insufflation of 10 mL of 30 μg/mL ozone (OI), or acupoint injection of 0.5 mL ozone (30 μg/mL; OA). ⋯ Two dogs treated with OA required rescue analgesia. Meloxicam, rectal insufflation of ozone and ozone injected into acupoints provided satisfactory analgesia for 24h in bitches undergoing elective OH. Ozone had no measurable adverse effects and is an alternative option to promote pain relief.
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The veterinary journal · Sep 2013
Clinical TrialEffects of fluid load on cardiovascular function during stepwise lung recruitment manoeuvre in healthy dogs.
The aim of this study was to evaluate the effects of a stepwise lung recruitment manoeuvre (RM) on cardiac output (CO) in mechanically ventilated dogs, with or without a previous fluid load. Eight healthy adult Beagle dogs were enrolled in a prospective crossover study. Following sedation with dexmedetomidine and methadone, anaesthesia was induced with propofol and maintained with isoflurane. ⋯ Compared to baseline, CO decreased during the RM in both groups. However, there was a significantly higher CO during the second RM at the highest pressure step (P<0.05) and during all decreasing pressure steps (P<0.05). In conclusion, a previous crystalloid fluid load could reduce the impact of a RM on CO in healthy dogs.
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The veterinary journal · Sep 2013
Validation of two behaviour-based pain scales for horses with acute colic.
Two behaviour-based scales for evaluating abdominal pain in horses (Equine Acute Abdominal Pain Scales, EAAPS-1 and -2) and a numerical rating scale (NRS) were compared for reliability and validity. Forty-one equine veterinarians randomly assigned into three groups were each presented a different set of 28 moving picture films randomly chosen among 36 films of horses with colic and four controls. One randomly chosen film was embedded twice within each set. ⋯ Both EAAPS scales discriminated well between extreme groups (areas under the receiver operating characteristic curve, ROC, area under the curve, AUC, >0.9) to differentiate severe from mild pain, as judged by the NRS. Both EAAPS scales showed predictive validity comparable to NRS (AUCs for dichotomous treatment modality (none and medically treated vs. surgically treated or euthanased) and with mortality (dead vs. alive) between 0.6 and 0.7 for all three scales. EAAPS-1 was the most reliable of the three scales and both EAAPS scales demonstrated validity comparable to the NRS scale.