Health technology assessment : HTA
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Health Technol Assess · Nov 2021
Randomized Controlled TrialUnicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting.
Although routine NHS data potentially include all patients, confounding limits their use for causal inference. Methods to minimise confounding in observational studies of implantable devices are required to enable the evaluation of patients with severe systemic morbidity who are excluded from many randomised controlled trials. ⋯ Further research is required to understand the performance of propensity score methods for evaluating surgical innovations and implantable devices.