Biochemical and biophysical research communications
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Biochem. Biophys. Res. Commun. · Mar 2010
Clinical TrialSerum miR-146a and miR-223 as potential new biomarkers for sepsis.
Current biomarkers cannot completely distinguish sepsis from systemic inflammatory response syndrome (SIRS) caused by other non-infectious diseases. Circulating microRNAs (miRNAs) are promising biomarkers for several diseases, but their correlation with sepsis is not totally clarified. ⋯ Serum miR-146a and miR-223 might serve as new biomarkers for sepsis with high specificity and sensitivity. (ClinicalTrials.gov number, NCT00862290.).