The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
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Int. J. Tuberc. Lung Dis. · Jan 2011
Smear-negative, culture-positive pulmonary tuberculosis among patients with chronic cough in Cotonou, Benin.
The main tuberculosis (TB) centre in Benin, West Africa, where only 2% of adult pulmonary TB cases are sputum smear-negative, all other pulmonary cases being smear-positive. ⋯ These results show the relatively low input of culture in TB diagnosis among chronic coughers in Cotonou, Benin, and demonstrates that the expected number of non-smear-positive TB cases in Benin is probably much lower than the World Health Organization's current annual estimates.
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Int. J. Tuberc. Lung Dis. · Jan 2011
Tuberculosis 'retreatment others': profile and treatment outcomes in the state of Andhra Pradesh, India.
The Government of India's Revised National Tuberculosis Control Programme (RNTCP), Andhra Pradesh, South India. ⋯ 'Retreatment others' were predominantly sputum smear-negative TB, with significantly better treatment outcomes than among smear-positive retreatment patients. Future studies may assess the accuracy of the diagnoses and factors contributing to the occurrence of 'retreatment others'.
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Int. J. Tuberc. Lung Dis. · Jan 2011
Comparative StudyPerformance comparison of four methods for detecting multidrug-resistant Mycobacterium tuberculosis strains.
National Tuberculosis Reference Laboratory, Kuwait. ⋯ Although gMTBDR(+) accurately detected ∼ 88% of MDR-TB strains, some rpoB mutations were either missed or were outside the region of analysis of the gMTBDR(+) assay.
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Int. J. Tuberc. Lung Dis. · Jan 2011
Drug susceptibility testing proficiency in the network of supranational tuberculosis reference laboratories.
The network of supranational tuberculosis reference laboratories (SRLs). ⋯ The rounds succeeded in comparing the proficiency of laboratories, and should be further promoted for DST quality assessment. However, to function with greater precision and to ultimately improve the clinical relevance of DST, the INH and RMP judicial result gold standard also needs to take into account genotypic and treatment outcome information.
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Int. J. Tuberc. Lung Dis. · Jan 2011
Intensified scale-up of public-private mix: a systems approach to tuberculosis care and control in India.
India's Revised National Tuberculosis Control Programme (RNTCP) implemented an intensified scale-up of public-private mix (PPM) DOTS covering 50 million population in 14 major cities. ⋯ The systems approach to the intensified PPM scale-up used in the 14 cities was productive. However, many challenges and barriers to scale-up of PPM DOTS in India remain.