The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
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Int. J. Tuberc. Lung Dis. · Aug 2011
Multicenter StudyDifferent therapeutic responses in chronic obstructive pulmonary disease subgroups.
Eleven referring hospitals in South Korea. ⋯ COPD subgroups classified by DL(CO) and RV/TLC may have different pulmonary function responses to pharmacological treatment.
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Int. J. Tuberc. Lung Dis. · Aug 2011
Multicenter StudyAcute respiratory distress syndrome caused by miliary tuberculosis: a multicentre survey in South Korea.
Miliary tuberculosis (TB) is an unusual cause of acute respiratory distress syndrome (ARDS). ⋯ ARDS caused by miliary TB was associated with a high in-hospital mortality rate, with SOFA score on the day of ARDS diagnosis being a valuable prognostic indicator.
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Int. J. Tuberc. Lung Dis. · Aug 2011
The impact of combined pulmonary fibrosis and emphysema on mortality.
The impact on patient mortality of combined pulmonary fibrosis and emphysema (CPFE) compared with emphysema alone has never been investigated. ⋯ CPFE is not rare and CPFE patients had a higher overall mortality risk than emphysema-only patients.
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Int. J. Tuberc. Lung Dis. · Jul 2011
Randomized Controlled TrialEarly bactericidal activity of delamanid (OPC-67683) in smear-positive pulmonary tuberculosis patients.
Delamanid (OPC-67683) is a novel mycolic acid biosynthesis inhibitor active against Mycobacterium tuberculosis at a low minimum inhibitory concentration. ⋯ Delamanid at all dosages was safe, well tolerated and demonstrated significant exposure-dependent EBA over 14 days, supporting further investigation of its pharmacokinetics and anti-tuberculosis activity.