The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
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Int. J. Tuberc. Lung Dis. · Nov 2018
Meta AnalysisAlcohol consumption and risk of tuberculosis: a systematic review and meta-analysis.
To perform a systematic review and meta-analysis of the association between alcohol consumption and risk of tuberculosis (TB). ⋯ Alcohol consumption is an important risk factor for the development of TB.
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Int. J. Tuberc. Lung Dis. · Aug 2014
Meta AnalysisSummarising published results from spirometric surveys of COPD: the problem of inconsistent definitions.
The use of different spirometric definitions for chronic obstructive pulmonary disease (COPD) has made an informative review of the available prevalence surveys impossible. ⋯ Using the BOLD data, we have been able to estimate COPD prevalences based on post-bronchodilator FEV1/FVC < LLN by adjusting estimates based on other common definitions, enabling more meaningful comparisons of published findings.
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Int. J. Tuberc. Lung Dis. · Apr 2014
Review Meta AnalysisValue of procalcitonin in differentiating pulmonary tuberculosis from other pulmonary infections: a meta-analysis.
To systematically and quantitatively summarise the current evidence on the utility of the procalcitonin test (PCT) in discriminating pulmonary tuberculosis (TB) from other pulmonary infections. ⋯ The results suggest consistently acceptable sensitivity and specificity of the PCT test in distinguishing TB from bacterial pneumonia. However, given the imperfect sensitivity and specificity of the test, medical decisions should be based on both the PCT test results as well as on clinical findings.
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Int. J. Tuberc. Lung Dis. · Apr 2012
Review Meta AnalysisLinezolid for the treatment of complicated drug-resistant tuberculosis: a systematic review and meta-analysis.
Current treatment for drug-resistant tuberculosis (DR-TB) is inadequate, and outcomes are significantly poorer than for drug-susceptible TB, particularly for patients previously treated with second-line drugs, treatment failures or extensively drug-resistant (XDR-) TB patients (complicated DR-TB). Linezolid is not recommended for routine DR-TB treatment due to the lack of efficacy data, but is suggested for patients where adequate second-line regimens are difficult to design. ⋯ Treatment success with linezolid was equal to or better than that commonly achieved for uncomplicated DR-TB, and better than previous reports for previously treated patients and those with XDR-TB. While data are limited, linezolid appears be a useful drug, albeit associated with significant adverse events, and should be considered in the treatment of complicated DR-TB.
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Int. J. Tuberc. Lung Dis. · Sep 2011
Meta AnalysisAttributable mortality of ventilator-associated pneumonia: a meta-analysis.
To investigate whether ventilator-associated pneumonia (VAP) is a true cause of mortality in the intensive care unit setting. ⋯ Presence, compared to absence, of VAP seems to be associated with higher mortality in critically ill patients. Appropriateness of initial antimicrobial treatment in such patients may moderate this association.