Clinical oral investigations
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Observational Study
Evaluation of oral manifestations of patients with mucopolysaccharidosis IV and VI: clinical and imaging study.
The aim of this study is to assess oral manifestations in patients with mucopolysaccharidosis IV (MPS IVA) and mucopolysaccharidosis VI (MPS VI). ⋯ The relevant frequency of MPS VI and IVA in the sample allows us to compare the changes occurring in both groups of patients, therefore enabling us to further comprehend the oral manifestations in specific types of MPS.
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Randomized Controlled Trial
Intravenous lidocaine for effective pain relief after bimaxillary surgery.
The aim of this prospective, randomized, double-blind, placebo-controlled study was to evaluate the analgesic effect of intravenous lidocaine on postoperative pain in bimaxillary surgery. ⋯ Systemic lidocaine is simple, economic, and a safe procedure reducing pain and soft tissue swelling after bimaxillary surgery.
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The purpose of this study was to assess the efficacy of different final irrigation activation methods in removing debris and smear layer in the apical, middle, and coronal portion of straight root canals. ⋯ The sonic activation system EDDY performed equally as well as PUI, and both methods were significantly superior compared with manual irrigation in straight root canals with regard to debris and smear layer removal.
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The nociceptive blink reflex (nBR) can be useful to investigate trigeminal nociceptive function. The aim of this study was to estimate the reliability of the nBR evoked by electrical stimulation of the three branches of the trigeminal nerve under the following conditions: over time (test-retest and intrarater reliability) and by two examiners (interrater reliability). ⋯ The nBR can be recommended as an electrophysiological technique to assess trigeminal nociceptive function.
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Retinol-binding protein 4 (RBP4) and leptin are both adipokines and involved in the pathophysiology of different vascular and inflammatory diseases and selectively elevated in patients with obesity. The aim of the present study was to determine and correlate the levels of RBP4 and leptin in gingival crevicular fluid (GCF) and serum in patients with chronic periodontitis (CP) and obesity. ⋯ RBP4 and leptin can be considered as possible GCF and serum markers of inflammatory activity in CP and obesity, which further longitudinal studies are needed.