Trends in cognitive sciences
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Trends Cogn. Sci. (Regul. Ed.) · Nov 2018
CommentUsing Anesthesia to Reveal the Elements of Consciousness.
General anesthesia provides an invaluable experimental tool to probe the essential neural circuits that underlie consciousness. A new study reports that cholinergic stimulation of the prefrontal cortex restores wake-like behaviors in anesthetized rodents, suggesting that cholinergic inputs to the prefrontal cortex play a fundamental role in modulating consciousness.