Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
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Randomized Controlled Trial Comparative Study
A randomized controlled trial to determine the lowest effective dose for adequate mydriasis in premature infants.
To compare the mydriatic efficacy of different numbers of eye drops for retinal examination of premature infants. ⋯ Effective mydriasis was achieved in the test eye with 1 or 2 drops and was sustained to 120 minutes. Therefore, retinal examinations could be completed by 90 minutes in most infants with the use of 1 drop. A larger study is needed to determine the effect of iris color and severity of ROP on these findings.