British journal of anaesthesia
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Randomized Controlled Trial Comparative Study
Randomized comparison of experts and trainees with nasal and oral fibreoptic intubation in children less than 2 yr of age.
We hypothesized that the time to successful fibreoptic tracheal intubation through the nasal route would be faster than the oral route for both experts and trainees in children <2 yr of age. ⋯ NCT02029300 (www.clinicaltrials.gov).
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Observational Study
Can remifentanil use in obstetrics be improved by optimal patient-controlled analgesia bolus timing?
The safety of patient-controlled i.v. analgesia (PCA) with remifentanil for obstetrical analgesia remains a matter of concern. The efficacy of remifentanil bolus application, that is, the coincidence between pain and remifentanil effect-site concentration, may be improved by forecasting contractions, but it is not known whether such a technique would also improve safety. ⋯ Because of the large variability of inter-contraction intervals, the use of prediction models will not influence the mean remifentanil concentration in-between contractions. Using models predicting future contractions to improve the timing of remifentanil PCA bolus administration will not diminish the need of continuous clinical surveillance and other safety measures.