British journal of anaesthesia
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Randomized Controlled Trial
Use of deep laryngeal oxygen insufflation during laryngoscopy in children: a randomized clinical trial.
Brief periods of haemoglobin oxygen desaturation are common in children during induction of general anaesthesia. We tested the hypothesis that oxygen insufflation during intubation slows desaturation. ⋯ NCT01886807.
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The association of patient expectations about recovery with the development of chronic post-surgical pain (CPSP) is uncertain. ⋯ NCT 00038129.
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Automated titration of propofol and remifentanil guided by the bispectral index (BIS) has been used for numerous surgical procedures. Orthotopic liver transplantation (OLT) uniquely combines major changes in circulating volume, an anhepatic phase, and ischaemia-reperfusion syndrome. We assessed the behaviour of this automated controller during OLT. ⋯ This pilot study indicates that automated titration of propofol and remifentanil guided by the BIS is feasible during OLT.
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The Acute Respiratory Distress Syndrome (ARDS) is a serious complication of major surgery and consumes substantial healthcare resources. Oesophagectomy is associated with high rates of ARDS. The aim of this study was to characterize patients and identify risk factors for developing ARDS after oesophagectomy. ⋯ Early and late ARDS after oesophagectomy increases intensive care and hospital length of stay. Given the high incidence of ARDS, cohorts of patients undergoing oesophagectomy may be useful as models for studies investigating ARDS prevention and treatment. Further investigations aimed at reducing perioperative ARDS are warranted.