British journal of anaesthesia
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Randomized Controlled Trial
Surgical pleth index in children younger than 24 months of age: a randomized double-blinded trial.
The surgical pleth index (SPI) is a measurement of intraoperative nociception. Evidence of its usability in children is limited. Given that the autonomic nervous system is still developing during the first years of life, the performance of the SPI on small children cannot be concluded from studies carried out in older age groups. ⋯ NCT02045810.
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Randomized Controlled Trial Comparative Study
Efficacy of pectoral nerve block versus thoracic paravertebral block for postoperative analgesia after radical mastectomy: a randomized controlled trial.
Pectoral nerve (PecS) block is a recently introduced technique for providing surgical anaesthesia and postoperative analgesia during breast surgery. The present study was planned to compare the efficacy and safety of ultrasound-guided PecS II block with thoracic paravertebral block (TPVB) for postoperative analgesia after modified radical mastectomy. ⋯ CTRI/2014/06/004692.
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Randomized Controlled Trial Comparative Study
A cadaver study comparing spread of dye and nerve involvement after three different quadratus lumborum blocks.
Posterior variants of abdominal wall block include the quadratus lumborum type I, quadratus lumborum type II and quadratus lumborum transmuscular blocks. Our objectives were to compare the spread of injectate and nerve involvement, after conducting blocks using ultrasound guidance in soft embalmed cadavers. ⋯ Consistent spread to lumbar nerve roots was achieved using the transmuscular approach through the quadratus lumborum.
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Randomized Controlled Trial Multicenter Study
Baroreflex impairment and morbidity after major surgery.
Baroreflex dysfunction is a common feature of established cardiometabolic diseases that are most frequently associated with the development of critical illness. Laboratory models show that baroreflex dysfunction impairs cardiac contractility and cardiovascular performance, thereby increasing the risk of morbidity after trauma and sepsis. We hypothesized that baroreflex dysfunction contributes to excess postoperative morbidity after major surgery as a consequence of the inability to achieve adequate perioperative tissue oxygen delivery. ⋯ ISCRTN76894700.
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Randomized Controlled Trial
Use of deep laryngeal oxygen insufflation during laryngoscopy in children: a randomized clinical trial.
Brief periods of haemoglobin oxygen desaturation are common in children during induction of general anaesthesia. We tested the hypothesis that oxygen insufflation during intubation slows desaturation. ⋯ NCT01886807.