British journal of anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Extradural bupivacaine or lignocaine anaesthesia for elective caesarean section: the role of maternal posture.
Extradural anaesthesia was induced in 64 patients in either the sitting or the lateral position, for elective Caesarean section with either 0.5% plain bupivacaine or 2% lignocaine with adrenaline 1 in 200,000. Onset was significantly shorter and a significantly greater number of patients were ready for surgery within 35 min following injection of lignocaine in the lateral position. ⋯ Significantly more patients who had received the first injection of local anaesthetic agent in the sitting position required ephedrine to correct maternal hypotension. Most frequently, hypotension coincided with transfer of patients to theatre and thus was associated with movement of the patient in the presence of extensive sympathetic block.
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Randomized Controlled Trial Clinical Trial
Magnesium and coronary revascularization.
Twenty patients, who underwent coronary revascularization without cardioplegic arrest, were given (during cardiopulmonary bypass) either magnesium chloride 16 mmol in 10 ml of water (magnesium group) or 10 ml of water alone (control group). Plasma and urinary magnesium concentrations were measured for 24 h after operation. ECG was recorded continuously during this period. ⋯ Urinary magnesium excretion was higher in the magnesium group, with 58% of the administered magnesium excreted in the first 24 h. The observed incidence of frequent or ventricular arrhythmias was 22% in the magnesium group compared with 63% in the control group. No significant differences in QTcorr intervals were observed between the groups.