British journal of anaesthesia
The most recent articles from:
Br J Anaesth
-
Orexin can facilitate emergence after general anaesthesia via multiple neural pathways. Dopaminergic neurones in the ventral tegmental area (VTA) participate in behavioural arousal from anaesthesia. We investigated the regulation of dopaminergic VTA neurones by orexinergic neurones during emergence from general anaesthesia. ⋯ Orexin promotes emergence from isoflurane anaesthesia through activation of dopaminergic neurones in the VTA.