International journal of clinical practice
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Int. J. Clin. Pract. · Oct 2000
ReviewSkeletal muscle relaxants: pharmacodynamics and pharmacokinetics in different patient groups.
Muscle relaxants can be safely administered during anaesthesia, providing the basic pharmacodynamic and pharmacokinetic characteristics of the compounds together with the physiological status of the patient are known. In this review the pharmacodynamics and pharmacokinetics of the neuromuscular blocking agents are discussed and related to the physical health or disease state of groups of patients.