International journal of clinical practice

The most recent articles from: Int. J. Clin. Pract. July 2013

Int. J. Clin. Pract. · Jul 2013

Comparative Study

Markers of insulin resistance and carotid atherosclerosis. A comparison of the homeostasis model assessment and triglyceride glucose index.

The present investigation was designed to test the association between carotid atherosclerosis and two simple markers of insulin resistance, i.e. HOMA-Index and TyG-Index. ⋯ The present findings suggest that TyG-Index is better associated with carotid atherosclerosis than HOMA-IR.

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Int. J. Clin. Pract. · Jul 2013

Comparative Study

Mirabegron for the treatment of overactive bladder: a prespecified pooled efficacy analysis and pooled safety analysis of three randomised, double-blind, placebo-controlled, phase III studies.

To examine pooled efficacy data from three, large phase III studies comparing mirabegron (50 and 100 mg) with placebo, and pooled safety data including additional mirabegron 25 mg and tolterodine extended release (ER) 4 mg results. ⋯ The efficacy and safety of mirabegron are demonstrated in this large pooled clinical trial dataset in patients with OAB.

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