International journal of clinical practice
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Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialComparison of the fracture strength of endodontically treated teeth restored with polyether ether ketone, zirconia and glass-fiber post-core systems.
This study aimed to compare the fracture resistance and fracture mode of maxillary central incisors restored with four different sizes and three different post-core systems. ⋯ PEEK post-cores showed sufficient fracture strength for the anterior region, similar to the other two post-core materials. PEEK post-cores showed more decementation and repairable fractures at lower forces, while restoration failure was mostly catastrophic for glass-fibre and zirconia posts.
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Int. J. Clin. Pract. · Sep 2021
Meta AnalysisMedication adherence to injectable glucagon-like peptide-1 (GLP-1) receptor agonists dosed once-weekly versus once-daily in patients with type 2 diabetes: a meta-analysis.
Suboptimal medication adherence has been associated with increased resource utilisation and mortality among patients with type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are becoming increasingly important in the treatment of T2D. However, medications in this class differ considerably in their dosing frequency, which may impact adherence. We sought to perform a meta-analysis to compare adherence to injectable GLP-1RAs dosed once weekly vs once daily in patients with T2D. ⋯ Once weekly dosing of injectable GLP-1RAs was associated with better adherence vs once daily dosing among patients with T2D. These findings coupled with the known detrimental consequences of non-adherence suggest that dosing frequency is an important factor to consider when selecting a GLP-1RA.
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Int. J. Clin. Pract. · Sep 2021
Meta AnalysisAdvisability of primary intraocular lens implantation for infants under 2: A systematic review and meta-analysis.
The present meta-analysis compared the postoperative visual performance of primary intraocular lens (IOL) implantation and primary aphakia in cataract infants. ⋯ For infants under 2 years of age, primary IOL implantation would provide more visual benefits compared with primary aphakia did, though the benefits would taper off with the age reaching 4.5 years. Moreover, the current study revealed a higher VAO incidence r in primary IOL implantation group.
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Int. J. Clin. Pract. · Sep 2021
Meta AnalysisLidocaine lubricant jelly does not reduce pain perception during female urethral catheterization: a systematic review with meta-analysis and trial sequential analysis.
The use of lubrication before performing urethral catheterization has been recommended. However, the benefit of using lidocaine gel over plain lubricant gel in reducing pain perception during female urethral catheterization is unclear. With this review, we aimed to compare the pain perception during female urethral catheterization with or without lidocaine lubricant gel. ⋯ The use of 2% lidocaine gel in female catheterization does not provide a significant reduction in pain perception as compared to plain lubricant gel.
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Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialComparison of serum dynamic thiol/disulfide homeostasis and nitric oxide levels of total intravenous versus inhaled anesthesia in endoscopic transsphenoidal pituitary surgery.
Transsphenoidal pituitary surgery (TPS) is traditionally performed under general anaesthesia. This study aimed to compare the effects of total intravenous anaesthesia (TIVA) or sevoflurane, an inhalation anaesthetic, on thiol-disulphide homeostasis in patients undergoing endoscopic endonasal TPS. ⋯ These results are the first to show that both TIVA and sevoflurane showed similar antioxidant effect with reduced disulphide levels, but sevoflurane may offer more robust oxidative stress protection and augmented NO production than TIVA during TPS. However, the clinical effect is needed to further investigate.