International journal of clinical practice
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Int. J. Clin. Pract. · Sep 2021
Impact of delay in cystoscopic surveillance on recurrence and progression rates in non-muscle invasive bladder cancer patients during COVID-19 pandemic.
To evaluate the impact of delay in cystoscopic surveillance on recurrence and progression rates in non-muscle-invasive bladder cancer (NMIBC). ⋯ This study showed that a 2-5 months of delay in follow-up cystoscopy increases the risk of recurrence by 2.4-fold, and delay in cystoscopy for more than 3 months increases the probability of progression by 6.7-fold. We suggest that cystoscopic surveillance should be done during the COVID-19 pandemic according to the schedule set by relevant guidelines.
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Int. J. Clin. Pract. · Sep 2021
Epidemiology of depression and anxiety among undergraduate students.
Depression and anxiety are the most common and prevalent mental health issues among undergraduate students. This study aimed to investigate the prevalence of anxiety and depression, their associated predictors, and to assess knowledge and use of antidepressant medications among university students in Jordan. ⋯ Findings of this study addressed the importance of taking serious measures and interventions to prevent the development of severe mental illness among university students.
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Int. J. Clin. Pract. · Sep 2021
A prospective cohort study of two predictor models for 30-day emergency readmission in older patients.
To undertake a prospective study of the accuracy of two models (LACE and BOOST) in predicting unplanned hospital readmission in older patients (>75 years). ⋯ In this prospective study, both the BOOST and LACE scores were found to be significant yet poor, predictive models of hospital readmission. Recent hospitalisation (within the previous 6 months) was found to be the most significant contributing factor.
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Int. J. Clin. Pract. · Sep 2021
Liothyronine and Levothyroxine Prescribing in England: A Comprehensive Survey and Evaluation.
The approach to thyroid hormone replacement varies across centres, but the extent and determinants of variation is unclear. We evaluated geographical variation in levothyroxine (LT4) and liothyronine (LT3) prescribing across General Practices in England and analysed the relationship of prescribing patterns to clinical and socioeconomic factors. ⋯ In spite of strenuous attempts to limit prescribing of liothyronine in general practice a significant number of patients continue to receive this therapy, although there is significant geographical variation in the prescribing of this as for levothyroxine, with specific general practice and CCG-related factors influencing prescribing of both levothyroxine and liothyronine across England.
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Int. J. Clin. Pract. · Sep 2021
Liver Stiffness is Associated with Disease Severity and Worse Clinical Scenarios in Coronavirus Disease 2019: A Prospective Transient Elastography Study.
Pre-existing chronic liver disease is currently considered a poor prognostic factor for coronavirus disease 2019 (COVID-19). The present study aimed to investigate the association of liver stiffness measurement (LSM) with disease severity and clinical course of COVID-19. ⋯ Initial VCTE application might help physicians identify patients who are more likely to have severe illness or worse clinical outcomes, in addition to other well-established clinical and laboratory factors. Further multicentre prospective studies are warranted to validate our results.