Pulmonary pharmacology & therapeutics
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Pulm Pharmacol Ther · Apr 2019
Vitamin D prevents experimental lung fibrosis and predicts survival in patients with idiopathic pulmonary fibrosis.
Vitamin D (VitD) is a steroid hormone with cytoprotective and anti-inflammatory properties. Epidemiological studies have suggested a link between VitD deficiency and risk of development of chronic lung diseases. Its role in lung fibrosis is largely unknown. The aim of our study was to investigate the role of VitD in experimental and human lung fibrosis. ⋯ VitD could serve as a prognosticator and potential therapeutic target in patients with IPF. Further studies are sorely needed.