The British journal of nutrition
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Comparative Study
Urea kinetics in healthy young women: minimal effect of stage of menstrual cycle, contraceptive pill and protein intake.
Urea kinetics were measured using prime/intermittent oral doses of [15N15N]urea, on five separate protocols in thirteen normal young women. Each woman underwent either two or three study protocols. Measurements were made at day 12 and day 22 of the menstrual cycle, whilst consuming their habitual protein intake in seven women not taking the contraceptive pill and in six women taking the contraceptive pill. ⋯ The variability was reduced on the controlled low intake of 55 g protein compared with the habitual intake. These results confirm the wide variability in aspects of urea kinetics between individuals. In women this variability is not, to any large extent, accounted for by changes associated with the menstrual cycle.