European journal of pain : EJP
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Migraine is an important source of social burden and work-related costs. Studies addressing the association of migraine with job stress are rare. ⋯ We observed a strong association between high-strain jobs and migraine. Job control was a stronger migraine-related factor for women. Low social support was associated with migraine in both sexes.
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No current standardized set of pelvic floor muscle (PFM) outcome measures have been specifically tested for their applicability in a general female chronic pelvic pain (CPP) population. We aimed to compare PFM function between a randomly selected population-based sample of women with CPP and age-matched pain-free controls using multiple standardized intravaginal examination measures recommended by the International Continence Society. ⋯ This controlled, single-blinded study with randomly selected participants provides new population-based information regarding associated PFM dysfunction in women with CPP using multiple intravaginal examination methods. However, to identify women with CPP who will benefit from a physiotherapeutic specialized intervention, future prospective randomized controlled trials using these reliable and predictive outcomes are needed.
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We investigated both the efficacy and the sub-chronic toxicity of Tephrosia toxicaria Pers. in the zymosan-induced temporomandibular joint (TMJ) inflammatory hypernociception in rats evaluating the possible role of heme oxygenase-1 (HO-1). ⋯ T. toxicaria did not produce any signs of toxicity and effectively decreased zymosan-induced TMJ inflammatory hypernociception dependent, at least in part, upon the HO-1 pathway integrity.
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The aim of this study was to investigate whether the perception of experimental pain was different during a mindfulness manipulation than during a distraction manipulation. Furthermore, it was examined if effects were moderated by dispositional pain catastrophizing. ⋯ The findings suggest that in persons with a high level of catastrophic thinking about pain, mindfulness-based coping may be a better approach than distraction.
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Chronic pain patients show increased peripheral activity when exposed to stimuli relevant to their pain problem. It has been suggested that in migraine there is a highly specific conditioning or sensitization to pain stimuli. The aims of this study were to analyse whether migraineurs (1) are sensitive not only to pain-related but also to other negative emotional words; and (2) show a memory bias for pain words, when compared to headache-free controls. ⋯ The findings suggest that in migraine, not only pain-related but also negative emotional words may act as triggers. These outcomes may have therapeutic implications as interventions could target problematic pain-related memories that influence migraine pain perception and pain-related physiological responses.