The British journal of surgery
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Meta Analysis Comparative Study
Laparoscopic versus open resection of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis.
The exact role of laparoscopic liver resection (LLR) in patients with hepatocellular carcinoma (HCC) and underlying liver cirrhosis (LC) is not well defined. In this meta-analysis, both long- and short-term outcomes following LLR versus open liver resection (OLR) were analysed. ⋯ Laparoscopic resection of HCC in patients with cirrhosis is associated with improved survival and perioperative outcomes.
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Meta Analysis Comparative Study
Neoadjuvant therapy versus direct to surgery for T4 colon cancer: meta-analysis.
Despite persistently poor oncological outcomes, approaches to the management of T4 colonic cancer remain variable, with the role of neoadjuvant therapy unclear. The aim of this review was to compare oncological outcomes between direct-to-surgery and neoadjuvant therapy approaches to T4 colon cancer. ⋯ Compared with direct to surgery, neoadjuvant therapy improves margin-negative resection rates and overall survival.
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The impact of acute pancreatitis in pregnancy on maternal and fetal outcomes is unclear. Historical case series document very poor outcomes, with maternal mortality rates of 20 per cent and fetal loss of 50 per cent. ⋯ This meta-analysis quantified both maternal and fetal outcomes following acute pancreatitis in pregnancy based on the concurrent literature. Maternal and fetal outcomes after acute pancreatitis in pregnancy have improved with advances in the management of pancreatitis.