Sleep & breathing = Schlaf & Atmung
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Randomized Controlled Trial Comparative Study
Comparison of three sedation regimens for drug-induced sleep endoscopy.
Drug-induced sleep endoscopy (DISE) allows for direct airway observation in patients with obstructive sleep apnea. This study compared the safety profiles and efficacies of three regimens for DISE. ⋯ The propofol-remifentanil combination was associated with a higher incidence of desaturation. The dexmedetomidine-remifentanil combination was associated with inadequate sedation in one half of the patients, even though it produced less respiratory depression. Addition of remifentanil reduced the cough reflex.
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Patients under treatment with continuous positive airway pressure (CPAP) may have residual sleep apnea (RSA). ⋯ The automatic analysis from auto-CPAP (S9 Autoset) showed a good diagnostic accuracy to identify residual sleep apnea. The absolute agreement between PSG and auto-CPAP to classify the respiratory events correctly varied from very low (obstructive apneas, hypopneas) to moderate (central apneas).