Current opinion in clinical nutrition and metabolic care
The most recent articles from:
September 2007
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Curr Opin Clin Nutr Metab Care · Sep 2007
ReviewInfluence of ghrelin on food intake and energy homeostasis.
The purpose of this review is to provide updated information on the role of ghrelin in food intake and energy homeostasis, and on its mechanism of action. Moreover, the potential of ghrelin as a target for drugs to treat cachexia and obesity will be discussed. ⋯ Ghrelin is an endogenous orexigenic peptide recently discovered in the stomach. Ghrelin is involved in short-term regulation of food intake since its plasma levels increase before meals and decrease strongly postprandially. Ghrelin is also involved in long-term body-weight regulation by inducing adiposity. Ghrelin might be useful for cachexia and obesity treatment.