Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Mar 2013
Randomized Controlled TrialA prospective, randomized, blinded study of continuous ropivacaine infusion in the median sternotomy incision following cardiac surgery.
The aim of this prospective, randomized, double-blind, placebo controlled trial was to evaluate the safety and efficacy of continuous ropivacaine infusion of into the sternal wound. ⋯ The phase III trial did not show improvement in time to extubation of the trachea or pain control in the 0.3% ropivacaine group, but it was stopped early by the data safety monitoring board.
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Reg Anesth Pain Med · Mar 2013
Randomized Controlled TrialThe effect of bench model fidelity on fluoroscopy-guided transforaminal epidural injection training: a randomized control study.
The purpose of this study was to determine whether high-fidelity simulators provide greater benefit than low-fidelity models in training fluoroscopy-guided transforaminal epidural injection. ⋯ Training an epidural procedure using a low-fidelity model may be equally effective as training on a high-fidelity model. These results are consistent with previous research on a variety of interventional procedures and further demonstrate the potential impact of simple, low-fidelity training models.
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Reg Anesth Pain Med · Mar 2013
Epinephrine administered with lidocaine solution does not worsen intrathecal lidocaine neurotoxicity in rats.
Epinephrine can potentially worsen the neurotoxic effects of local anesthetics when used for spinal or epidural anesthesia. The vasoconstrictive property of epinephrine reduces dural blood flow, which in turn reduces the clearance of local anesthetics from the subarachnoid space. This study examined the histological and neurofunctional effects of intrathecally administered lidocaine combined with epinephrine in rats. ⋯ Intrathecal epinephrine prolonged the action of intrathecal lidocaine but did not worsen lidocaine-induced histological damage and functional impairment.
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Reg Anesth Pain Med · Mar 2013
Inflammatory response after injection of aqueous gel into subarachnoid space in piglets.
Ultrasound-guided neuraxial anesthesia requires the application of ultrasound gel between the transducer and the skin to avoid signal drop-off. As the needle is inserted, the gel may be introduced intrathecally. The purpose of this study was to examine the evidence of an inflammatory response in the subarachnoid space after intrathecal gel introduction. ⋯ Subarachnoid injection of ultrasound gel in piglets results in an inflammatory response within neuraxial space.