Journal of clinical monitoring and computing
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J Clin Monit Comput · Oct 2010
Assessment of the effect of rapid crystalloid infusion on stroke volume variation and pleth variability index after a preoperative fast.
Stroke volume variation (SVV) during controlled mechanical ventilation is a useful predictor in response to volume expansion, and pleth variability index (PVI), a novel algorithm allowing for automated and continuous calculation of the respiratory variations in the pulse oximeter waveform amplitude, can also predict fluid responsiveness non-invasively in mechanically ventilated patients. The aim of this study was (1) to determine whether acute fluid infusion affects SVV and PVI, and (2) to compare the two values in the case of acute fluid infusion after a preoperative fast following general anesthesia induction. ⋯ A rapid infusion of 250-500 ml of a crystalloid in nearly healthy subjects who had fasted overnight returned their SVV to within the normal range. In such cases, SVV is a more sensitive predictor of fluid responsiveness than is PVI, and the infusion gradually increased SVI.
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J Clin Monit Comput · Oct 2010
Clinical TrialReversal of neuromuscular blockade by sugammadex does not affect EEG derived indices of depth of anesthesia.
According to previous studies neuromuscular blockade may affect the depth of anesthesia. One theory states that neuromuscular blockade prevents disturbing EMG signals, arousing from the muscles of the forehead, from falsely elevating bispectral index (BIS)-levels. According to the afferentation theory signals generated in muscle stretch receptors, accessing the brain through afferent nerve pathways, induce arousal. By blocking these signals neuromuscular blockade would increase depth of anesthesia. Arousal has previously been associated with neostigmine reversal. This study investigates the possible effect of sugammadex on the level of anesthesia as defined by BIS and spectral entropy levels. ⋯ Sugammadex does not affect level of anesthesia as determined by BIS or entropy levels.
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J Clin Monit Comput · Oct 2010
Novel automatic endotracheal position confirmation system: mannequin model algorithm evaluation.
A novel endotracheal intubation accurate positioning confirmation system based on image classification algorithm is introduced and evaluated using a mannequin model. ⋯ This fully automatic image recognition system was used successfully to discriminate airway carina and non-carina endotracheal tube positioning. The system had a 100% success rate using a mannequin model and therefore further investigation including live tissue model and human research should follow.