Journal of clinical monitoring and computing
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J Clin Monit Comput · Jun 2022
ReviewPower spectrum and spectrogram of EEG analysis during general anesthesia: Python-based computer programming analysis.
The commonly used principle for measuring the depth of anesthesia involves changes in the frequency components of the electroencephalogram (EEG) under general anesthesia. Therefore, it is essential to construct an effective spectrum and spectrogram to analyze the relationship between the depth of anesthesia and the EEG frequency during general anesthesia. This paper reviews the computer programming techniques for analyzing the spectrum and spectrogram derived from a single-channel EEG recorded during general anesthesia. ⋯ Finally, the multitaper method, which can suppress artifacts caused by the edges of the analysis segments, suppress noise, and probabilistically infer values that are close to the real power spectral density, is explained using practical examples of the analysis. All analyses were performed and all graphs plotted using Python under Jupyter Notebook. The analyses demonstrated the effectiveness of Python-based programming under the integrated development environment Jupyter Notebook for constructing an effective spectrum and spectrogram for analyzing the relationship between the depth of anesthesia and EEG frequency analysis in general anesthesia.
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J Clin Monit Comput · Jun 2022
Clinical TrialIncongruous effect of phenylephrine on changes in cerebral blood volume measured by near-infrared spectroscopy (NIRS) indicating extracranial contamination.
We assessed extracranial contamination of the near-infrared spectroscopy (NIRS) signal during administration of phenylephrine. The study was performed with NIRO 200NX which employs both the Modified Beer-Lambert (MBL) method to measure total hemoglobin (tHb, expressed in µM), and Spatially Resolved Spectroscopy (SRS) to measure total hemoglobin content (nTHI, expressed in arbitrary units (a.u.)). SRS tends to not be affected by extracranial blood flow. ⋯ The median difference between the Z-scores of nTHI and tHb was - 0.02 [95%CI - 0.04 to - 0.003] (p = 0.03), with a higher variability in the Z-scores of tHb. Phenylephrine induced significant larger changes in MBL values compared to SRS values, indicating that the MBL method might be more prone to extracranial contamination. Trial and clinical registry: Trial registration number: B670201939459, ethical committee number: 2019/0265, date of approval: March 19, 2019.
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J Clin Monit Comput · Jun 2022
Intraoperative impaired cerebrovascular autoregulation and delayed neurocognitive recovery after major oncologic surgery: a secondary analysis of pooled data.
Cerebral blood flow is tightly regulated by cerebrovascular autoregulation (CVA), and intraoperative impairment of CVA has been linked with perioperative neurocognitive disorders. We aim to assess whether impairment of CVA during major oncologic surgery is associated with delayed neurocognitive recovery (DNCR) postoperatively. We performed a secondary analysis of prospectively collected data. ⋯ Intraoperative impairment of CVA is associated with postoperative neurocognitive function early after oncologic surgery. Therefore, intraoperative monitoring of CVA may be a target for neuroprotective interventions. The initial studies were retrospectively registered with primary clinical trial registries recognized by the World Health Organization (ClinicalTrials.gov Identifiers: DRKS00010014, 21.03.2016 and NCT04101006, 24.07.2019).
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J Clin Monit Comput · Jun 2022
Observational StudyBioreactance-derived haemodynamic parameters in the transitional phase in preterm neonates: a longitudinal study.
Bioreactance (BR) is a novel, non-invasive technology that is able to provide minute-to-minute monitoring of cardiac output and additional haemodynamic variables. This study aimed to determine the values for BR-derived haemodynamic variables in stable preterm neonates during the transitional period. A prospective observational study was performed in a group of stable preterm (< 37 weeks) infants in the neonatal service of Tygerberg Children's Hospital, Cape Town, South Africa. ⋯ To our knowledge, this is the first paper to present longitudinal BR-derived haemodynamic variable data in a cohort of stable preterm infants, not requiring invasive ventilation or inotropic support, during the first 72 h of life. Bioreactance-derived haemodynamic monitoring is non-invasive and offers the ability to simultaneously monitor numerous haemodynamic parameters of global systemic blood flow. Moreover, it may provide insight into transitional physiology and its pathophysiology.
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J Clin Monit Comput · Jun 2022
The effect of COVID-19 epidemic on vital signs in hospitalized patients: a pre-post heat-map study from a large teaching hospital.
The Lombardy SARS-CoV-2 outbreak in February 2020 represented the beginning of COVID-19 epidemic in Italy. Hospitals were flooded by thousands of patients with bilateral pneumonia and severe respiratory, and vital sign derangements compared to the standard hospital population. We propose a new visual analysis technique using heat maps to describe the impact of COVID-19 epidemic on vital sign anomalies in hospitalized patients. ⋯ COVID-19 epidemic profoundly affected the incidence of severe derangements in vital signs in a large academic hospital. We validated heat maps as a method to analyze the clinical stability of hospitalized patients. This method may help to improve resource allocation according to patient characteristics.