Journal of clinical monitoring and computing
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J Clin Monit Comput · Apr 2015
Comparative StudyComparison of two devices using near-infrared spectroscopy for the measurement of tissue oxygenation during a vascular occlusion test in healthy volunteers (INVOS(®) vs. InSpectra™).
The aim of this study was to compare tissue oxygen saturation as measured by INVOS® and InSpectra™ during a vascular occlusion test (VOT) in the same subject. Twenty healthy adults were investigated. The INVOS® and InSpectra™ probes were placed randomly on the right and left thenar eminence in the same participant and monitoring of tissue oxygen saturation (SrO2 from INVOS® and StO2 from InSpectra™) were begun. ⋯ SrO2 declined to 40% more rapidly than did the StO2 (147±38 vs. 199±41 s, p<0.01). The deoxygenation and reoxygenation rates were higher (p<0.01) and the reactive hyperemic area was more extensive for INVOS® than for InSpectra™ (p=0.015). In conclusion, the VOT on the thenar muscle using INVOS® was as clinically applicable as InSpectra™, but baseline values and dynamic changes of INVOS® differed from those of InSpectra™.
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J Clin Monit Comput · Apr 2015
ReviewIntrathecal drug delivery for chronic pain management-scope, limitations and future.
Intrathecal drug delivery system (IDDS) is a targeted therapy system for treating pain and muscle spasm. IDDS is recommended for the treatment of chronic pain which does not respond to optimal medical management. The aim of this review article is to give an up to date and concise account of the use of IDDS. ⋯ IDDS is an invasive technique, which can result in severe morbidity and mortality. The up to date knowledge gained from this article along with the recommendations for improving safety in patients receiving IDDS, makes it a valuable resource for healthcare practitioners. Continued research, including outcome studies of this therapy continues to be necessary.
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J Clin Monit Comput · Apr 2015
Clinical TrialEstimation of shunt fraction by transesophageal echocardiography during one-lung ventilation.
As the blood flow volume in non-dependent lung composed the primary part of the intrapulmonary shunt during one-lung ventilation (OLV), the shunt fraction (SF) during OLV can be represented by the ratio of blood flow volume in non-dependent lung to the bilateral lung. The purpose of this study is to estimate the shunt in non-dependent lung by transesophageal echocardiography (TEE). Fifteen adult patients requiring OLV for thoracic surgery were enrolled in the study. ⋯ There was significant liner correlation between SF and PaO2 (r=0.717), and between BFP and PaO2 (r=0.593). It is feasible to estimate intrapulmonary shunt by TEE in anesthetized patients undergoing OLV. SF measured by TEE has significant correlation with PaO2, and it would expected to be used to predict hypoxemia during OLV.