Comprehensive psychiatry
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Comprehensive psychiatry · Nov 2019
Meta AnalysisCombination therapy of varenicline and bupropion in smoking cessation: A meta-analysis of the randomized controlled trials.
The effects of the combination therapy of varenicline and bupropion in smoking cessation are still controversial. ⋯ Compared with varenicline monotherapy, combination treatment with varenicline and bupropion can significantly improve the abstinence rate at the end of treatment and 6months follow-up, mainly in highly dependent smokers and heavy smokers.