Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
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Randomized Controlled Trial
Clinical impact of rapid molecular detection of respiratory pathogens in patients with acute respiratory infection.
Acute respiratory infections (ARI) are a leading cause of morbidity and mortality worldwide. There is a need to demonstrate the clinical impact of using the new, rapid and sensitive molecular assays in prospectively designed studies. ⋯ The high respiratory viruses' detection rate and availability of results within two hours when using FilmArray-RP were associated with decreases in antibiotic prescriptions and complementary studies and more accurate use of oseltamivir.
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Observational Study
Using a novel rapid viral test to improve triage of emergency department patients with acute respiratory illness during flu season.
Acute respiratory illnesses (ARI) are mostly viral in etiology and cause significant morbidity and mortality. Point of care PCR (POC-PCR) is a promising new technology for rapid virus identification but utility in the Emergency Department (ED) is not yet defined. ⋯ Rapid POC-PCR for influenza and RSV in ED triage has excellent sensitivity and specificity and the potential to improve social distancing practices through better triage and increase appropriate prescription of antimicrobials.