Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
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Limited research exists about the possible cardiovascular effects of electronic nicotine delivery systems (ENDS). We therefore sought to compare exposure to known or potentially cardiotoxic volatile organic compounds (VOCs) in ENDS users, smokers, and dual users. ⋯ ENDS use in conjunction with other tobacco products may not significantly reduce exposure to VOC, but sole use does generally reduce some VOC exposure and warrants more in-depth studies.
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Understanding the neural mechanisms that support successful smoking cessation is vital to the development of novel treatments for nicotine dependence. ⋯ The submitted research is a novel contribution to the study of successful nicotine abstinence, in part, because it includes individuals who have successfully overcome nicotine dependence. The use of ICA allowed for examination of large-scale resting-state networks throughout the brain without the need for specifying numerous regions of interest. This research supports the view that overcoming nicotine dependence may depend on reducing spontaneous activity in posterior regions of the brain rather than solely enhancing frontal control.