Canadian journal of physiology and pharmacology
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Can. J. Physiol. Pharmacol. · Apr 2015
Protective effects of baicalin on LPS-induced injury in intestinal epithelial cells and intercellular tight junctions.
To investigate the protective effects and mechanisms of baicalin on lipopolysaccharide (LPS)-induced injury in intestinal epithelial cells and intercellular tight junctions. ⋯ Baicalin has the capacity to protect IEC-6 cells and the intercellular tight junctions from LPS-induced injury. The mechanisms may be associated with inhibiting the production of inflammatory cytokines, and up-regulating the mRNA and protein expression of ZO-1.