Hell J Nucl Med
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The term "Subjective Cognitive Impairment (SCI)" is the most widely accepted term for cognitive complaints of otherwise apparently healthy older adults. It is presently clear that SCI might be a risk factor for the development of Mild Cognitive Impairment and dementia. As regards SCI measurement and potential diagnosis, several studies showed that SCI is a condition in which people score in the normal range on common tests but believe they experience cognitive decline. Hence, to assess the characteristic of the SCI subtle cognitive decline, self-report measures were developed to estimate "self-experience" of minimal decline in cognition seem the most appropriate tools. In this vein, the present study aimed at examining the capacity of the Greek version of two self-report instruments of the aforementioned type to detect SCI in community dwelling older adults. ⋯ Self-report questionnaires of "everyday" cognitive and memory failures seem to be associated with specific objective tests of cognition in aging. Hence, they are useful tools for detecting early cognitive impairment at least in older adults. Their administration together with objective cognitive tasks of high difficulty could substantially help for SCI screening. Given that there is also evidence that the experience of subtle impairment in cognition is related to increased likelihood of biomarker abnormalities indicative of AD pathology, the assessment of subjective estimations is revealed as a useful primary indicator of early AD effects on cognitive functioning.
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Adult liver Langerhans cell histiocytosis (LCH) is an extremely rare desease. This paper reports a 40 years old male patient who was diagnosed as liver LCH though ultrasound-guided liver biopsy. The initial Fluorrine-18- fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) showed multiple nodular low-density lesions in liver without obvious elevated 18F-FDG uptake. Four years later, the follow-up 18F-FDG PET/CT showed the liver multiple lesions with slightly elevated 18F-FDG uptake. ⋯ We describe this case, to highlight the importance of 18F-FDG PET/CT in differential diagnosis for the primary disease and the multiple liver nodules.
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The study evaluated the significance of 18F fluorodeoxyglucose (18F-FDG) uptake of bone marrow (BM) for predicting progression-free survival (PFS) in lymphoma patients without BM involvement. ⋯ In lymphoma patients without BM involvement, 18F-FDG uptake of BM was significantly associated with worse PFS. Patients with high 18F-FDG uptake of BM showed similar prognosis to those with BM involvement.
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The Hellenic Journal of Nuclear Medicine is about to celebrate its 20th anniversary end of 2017. On board of the editorial team since 2003, this journal has influenced me like a good friend over the many past years. From time to time, the journal has published interesting and valuable historical notes. ⋯ Laios, M. Zozoglou. 2017; 20(1): Ahead of print. And hopefully many more to follow!
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Differentiation of vertebral metastases from Schmorl's nodes, especially with fluorine-18-fluorodeoxyglucose (18F-FDG) uptake, is very important for the appropriate management of these patients in case they have malignancy. We aimed to evaluate the value of 18F-FDG positron emission tomography/computed tomography (PET/CT) in differentiating vertebral metastases from Schmorl's nodes with 18F-FDG uptake. ⋯ Although the SUVmax in the Schmorl's nodes and vertebral metastases was similar, the 18F-FDG distribution characteristic in PET/CT can help differentiating the vertebral metastases from Schmorl's.