J Radiol
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Review
[Prevention of severe reactions after iodinated contrast media injection: review of the literature].
One of the goal of a premedication before contrast agent injection is to decrease their adverse effects. However, no randomized study was published to date on the value of a systematic premedication for the prevention of immediate severe reactions. A knowledge of pathophysiological mechanisms and patients at risk seems to be essential. ⋯ Indeed, measurement of specific IgEs has not been validated for contrast media. The test dose should be discarded because it is a false security. The eventuality of adverse effects of the drugs used for premedication should not be underestimated.