Clinical pharmacology and therapeutics
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Clin. Pharmacol. Ther. · Jun 1998
Randomized Controlled Trial Clinical TrialIntermittent dobutamine treatment in patients with chronic refractory congestive heart failure: a randomized, double-blind, placebo-controlled study.
Intravenous dobutamine administration improves short-term hemodynamics in patients with severe congestive heart failure (CHF). However, the clinical benefit of periodic administration remains controversial. ⋯ Intermittent dobutamine infusions in patients with refractory CHF have no effect on the need for hospitalization or on survival.