Clinical pharmacology and therapeutics
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Clin. Pharmacol. Ther. · May 2001
Randomized Controlled Trial Clinical TrialIntravenous magnesium sulfate for bronchial hyperreactivity: a randomized, controlled, double-blind study.
Magnesium has been shown to be helpful in the treatment of acute exacerbations of asthma. Conflicting data exist concerning the effect of magnesium on bronchial hyperreactivity. ⋯ In the magnesium group, 30% of the subjects reached a normal PC(20) compared with 10% in the placebo group. We conclude that intravenous magnesium sulfate significantly improved bronchial hyperreactivity and may serve as an adjunct to standard treatment.