Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
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A 63-year old women developed livedo reticularis during treatment with amantadine. This reversible side effect of amantadine has been most often seen in women and is frequently associated with persistent ankle edema. We discuss the signs and symptoms, pathogenesis and treatment of amantadine-induced livedo reticularis.