Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
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Comparative Study
[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
Stage IV melanoma patients with a very advanced disease are usually excluded from clinical trials. We treated 25 stage IV patients with temozolomide - a cytostatic drug with 100% oral bioavailability and considerable penetration of CNS tissue. ⋯ Temozolomide represents a safe treatment option in patients with metastatic melanoma and poor prognosis.