Neural Regen Res
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To evaluate the effectiveness and safety of the Xingnao Kaiqiao needling method for treating acute ischemic stroke. ⋯ The Xingnao Kaiqiao needling method is effective and safe for acute ischemic stroke. However, there was selective bias in this study, and the likelihood of measurement bias is high. Thus, more high-quality randomized controlled trials are needed to provide reliable evidence of the efficacy and safety of Xingnao Kaiqiao acupuncture in the treatment of acute ischemic stroke.