Fertility and sterility
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Fertility and sterility · Feb 2015
Comparative Study Observational StudyEach small antral follicle in ovaries of women with polycystic ovary syndrome produces more antimüllerian hormone than its counterpart in a normal ovary: an observational cross-sectional study.
To ascertain if subfertile women with polycystic ovary syndrome (PCOS) secrete more antimüllerian hormone (AMH) per antral follicle than control women. ⋯ Subfertile women with PCOS secrete significantly more AMH per antral follicle than women with PCOM only and control women.
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Fertility and sterility · Feb 2015
Randomized Controlled TrialNovel topical formulation of lidocaine provides significant pain relief for intrauterine device insertion: pharmacokinetic evaluation and randomized placebo-controlled trial.
To investigate the pharmacokinetics, safety, and analgesic efficacy of a novel topical formulation of lidocaine at insertion of an intrauterine device (IUD). ⋯ 2011-005660-18 and 2011-006220-20 (EudraCT).
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Fertility and sterility · Feb 2015
Clinical TrialSurgical treatment affects perceived stress differently in women with endometriosis: correlation with severity of pain.
To investigate the amount of perceived stress in a group of women with different forms of endometriosis-related pain before and after surgical treatment. ⋯ Patients with deep endometriosis-related pain (dysmenorrhea, pelvic pain, dyspareunia) showed the highest level of perceived stress, which significantly decreased after surgical treatment.
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Fertility and sterility · Feb 2015
First systematic experience of preimplantation genetic diagnosis for single-gene disorders, and/or preimplantation human leukocyte antigen typing, combined with 24-chromosome aneuploidy testing.
To study the feasibility, accuracy, and reproductive outcome of 24-chromosome aneuploidy testing (24-AT), combined with preimplantation genetic diagnosis (PGD) for single-gene disorders (SGDs) or human leukocyte antigen (HLA) typing in the same biopsy sample. ⋯ The introduced combined approach is a potential universal PGD test, which in addition to achieving extremely high diagnostic accuracy, significantly improves reproductive outcomes of PGD for SGDs and HLA typing in patients of advanced reproductive age.