Adv Clin Exp Med
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Rivaroxaban (Xarelto) does not require routine coagulation monitoring; however, in certain clinical situations (overdose, drug accumulation, urgent surgery) measurement of its plasma concentration is highly recommended. Currently, there is no single hemostasis test that shows a direct correlation between rivaroxaban plasma levels and anticoagulant efficacy. ⋯ PT demonstrated better diagnostic value than APTT in rivaroxaban administration. The ROTEM clotting time (CT) according to EXTEM may be used to determine the anticoagulation effect of rivaroxaban, but is not sensitive enough to measure the residual activity of this drug.
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Head injuries in elderly people are a common cause of hospitalization at emergency departments. This group of patients is at high risk of post-traumatic intracranial pathology, which is diagnosed by computed tomography (CT) scanning of the head. ⋯ Ground-level falls are the most frequent mechanism of head trauma in older people. One of the most commonly identified mechanisms of a fall is TLOC. Head injuries due to TLOC entailed a high risk of intracranial pathology in the elderly population. The risk of trauma-related positive CT scans in patients with unexplained falls is high, and is similar to that observed in patients with TLOC. The highest risk of trauma-related positive CT scans is observed in patients who have suffered a high-energy trauma.
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Clinical Trial
Evaluation of a Home-Based Pulmonary Rehabilitation Program for Older Females Suffering from Bronchial Asthma.
Asthma is a disease that affects people of all ages worldwide. ⋯ The home-based pulmonary rehabilitation program significantly improved all respiratory function parameters. The patients' PImax scores also significantly improved. Among the physical fitness parameters, the 6MWT and lower body flexibility trials significantly improved. The home-based pulmonary rehabilitation program can be used effectively in patients suffering from bronchial asthma.
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Psychological factors are one of many that contribute to the increased risk of a psychiatric disorder's occurrence after childbirth. ⋯ In the first week after childbirth, one-fourth of women are in danger of the occurrence of mood disorders. There is a negative correlation between the sense of self-efficacy and dispositional optimism and risk of occurrence of mood disorders after childbirth.