Iran J Basic Med Sci
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Iran J Basic Med Sci · Jan 2014
Evaluation of immune response after moderate and overtraining exercise in wistar rat.
The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study. ⋯ These data confirm a positive effect of moderate exercise on immune function and a decrease in susceptibility to viral infection by inducing Th1 cytokine profile shift. However, prolonged and overtraining exercise causes numerous changes in immunity that possibly reflects physiological stress and immune suppression.