Orphanet J Rare Dis
-
Orphanet J Rare Dis · May 2018
Epidemiology of Bradykinin-mediated angioedema: a systematic investigation of epidemiological studies.
Bradykinin-mediated angioedema (Bk-AE) can be life-threatening and requires specific targeted therapies. Knowledge of its epidemiology may help optimize its management. ⋯ Epidemiological evidence on Bk-AE is limited to North America and Europe. ACEI-AE is more common than C1-INH-HAE (~ 10:1), which is more common than C1-INH-AAE (~ 10:1). More studies are needed to comprehensively assess the epidemiological burden of Bk-AE.